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Each vial ships with structural data and lot identifiers for the compound, plus a Certificate of Analysis documenting purity and identity. Ready for the bench. Synthesized via solid-phase peptide synthesis (SPPS), purified by reverse-phase HPLC, verified by mass spectrometry, and tested for sterility and endotoxin load. Every spec is documented on the signed Certificate of Analysis that ships with your vial.
Sermorelin (GHRH[1-29]-NH₂) is a synthetic 29-amino acid peptide comprising the first 29 residues of endogenous growth hormone-releasing hormone (GHRH), sufficient for full biological activity at the GHRH receptor. It entered clinical investigation in the 1980s as a diagnostic tool for GH deficiency.
Sermorelin binds to the GHRH receptor (GHRHR) on anterior pituitary somatotrophs, stimulating pulsatile GH release and downstream IGF-1 production. Unlike exogenous GH, sermorelin preserves the endogenous pulsatile GH secretion pattern and remains subject to normal feedback regulation via somatostatin. Published research has examined sermorelin in GH deficiency diagnosis, pediatric growth failure, adult GH deficiency, and age-related GH decline.
Sermorelin acetate (Geref) was FDA-approved as a diagnostic agent; it was later withdrawn from the US market for commercial, not safety, reasons. This product is for laboratory research use only.
Walker RF (2006) · Rejuvenation Res
Sermorelin: A better approach to management of adult-onset growth hormone insufficiency?
PubMed · PubMed · 16706635Prakash A, Goa KL (1999) · Drugs
Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency
PubMed · PubMed · 1020030310mg / single compound
10mg / single compound
10mg / single compound
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