Each blend vial ships with structural data and lot identifiers for both peptides, plus a single Certificate of Analysis documenting per-component purity and the blended composition. Pre-mixed for the bench. Both peptides are synthesized via solid-phase peptide synthesis (SPPS), purified independently by reverse-phase HPLC, and combined in a single vial at a verified ratio. Mass spectrometry confirms identity for each component, and sterility plus endotoxin testing applies to the final blend.
SEMAX (Ac-Met-Glu-His-Phe-Pro-Gly-Pro) is a synthetic heptapeptide derived from the adrenocorticotropic hormone (ACTH 4-10) fragment, developed at the Institute of Molecular Genetics of the Russian Academy of Sciences in the late 1980s. Registered as a pharmaceutical in Russia and Ukraine for neurological indications including ischemic stroke. SEMAX is reported to modulate BDNF and NGF expression in CNS tissue models and has been studied in neurotrophin signaling, cognitive function, and neuroprotection in rodent models.
SELANK (Thr-Lys-Pro-Arg-Pro-Gly-Pro) is a synthetic heptapeptide analog of the endogenous immunopeptide tuftsin (Thr-Lys-Pro-Arg), also developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. Registered as an anxiolytic pharmaceutical in Russia. SELANK is reported to modulate GABAergic neurotransmission, enkephalin degradation, and BDNF expression in CNS models.
All findings referenced here derive from preclinical models. These compounds are not approved by the FDA for any use. Research use only.
Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus
PubMed · PubMed · 16677804Effects of the heptapeptide selank on the content of monoamines and their metabolites in the brain of BALB/c and C57BL/6 mice: a comparative study
PubMed · PubMed · 1824046110mg / single compound
10mg / single compound
10mg / single compound
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