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Each vial ships with structural data and lot identifiers for the compound, plus a Certificate of Analysis documenting purity and identity. Ready for the bench. Synthesized via solid-phase peptide synthesis (SPPS), purified by reverse-phase HPLC, verified by mass spectrometry, and tested for sterility and endotoxin load. Every spec is documented on the signed Certificate of Analysis that ships with your vial.
Melanotan II (MT-II; Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂) is a synthetic cyclic analog of alpha-melanocyte-stimulating hormone (α-MSH). It was developed at the University of Arizona in the early 1990s by Victor Hruby and colleagues as part of a program to identify potent, metabolically stable melanocortin receptor agonists.
MT-II binds with high affinity to melanocortin receptors MC1R, MC3R, MC4R, and MC5R. Published preclinical studies have examined MT-II’s effects on penile erection via MC4R activation in the CNS (Dornan et al., 1996; Wessells et al., 1998), skin pigmentation via MC1R, and appetite suppression via MC3R/MC4R pathways.
All findings referenced here derive from preclinical models or early-phase clinical studies and have not been validated in large controlled clinical trials. Melanotan II is not approved by the FDA for any diagnostic, therapeutic, or preventive application. Research compound only.
Wessells H, et al. (1998) · J Urol
Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction
PubMed · PubMed · 9783924Dorr RT, et al. (1996) · Life Sci
Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study
PubMed · PubMed · 892020310mg / single compound
10mg / single compound
10mg / single compound
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