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Each vial ships with structural data and lot identifiers for the compound, plus a Certificate of Analysis documenting purity and identity. Ready for the bench. Synthesized via solid-phase peptide synthesis (SPPS), purified by reverse-phase HPLC, verified by mass spectrometry, and tested for sterility and endotoxin load. Every spec is documented on the signed Certificate of Analysis that ships with your vial.
Tesamorelin is a synthetic 44-amino-acid analog of growth hormone-releasing hormone (GHRH). The N-terminus carries a stabilizing trans-3-hexenoyl modification that resists enzymatic degradation by dipeptidyl peptidase-IV (DPP-IV), extending its functional half-life relative to native GHRH(1-44).
Tesamorelin is notable as the only GHRH-analog peptide approved by the FDA for any indication — originally for the reduction of excess abdominal fat in HIV-associated lipodystrophy under the brand name Egrifta (Theratechnologies). Outside that approved use, the compound remains a research compound.
In the published preclinical and clinical literature, Tesamorelin is most-cited alongside investigations of the GH/IGF-1 axis, visceral adipose tissue biology, hepatic fat metabolism, lipid profile modulation, and pulsatile somatotropic signaling. Use outside the approved indication has not been evaluated by the FDA.
Falutz J, et al. (2010) · J Clin Endocrinol Metab
Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in HIV-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials
PubMed · PubMed · 20338859Stanley TL, et al. (2012) · Clin Infect Dis
Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial
PubMed · PubMed · 2226771610mg / single compound
10mg / single compound
10mg / single compound
Native human GHRH(1-44) is rapidly degraded by the enzyme dipeptidyl peptidase-IV (DPP-IV), which cleaves it within minutes of release into circulation. Tesamorelin adds a trans-3-hexenoyl group at the N-terminus, blocking DPP-IV cleavage and extending the functional half-life of the peptide. The amino acid sequence remains otherwise identical to native GHRH — Tesamorelin acts on the same GHRH receptor with the same downstream pharmacology.
Tesamorelin is the only GHRH-analog peptide approved by the FDA for any indication — originally for the reduction of excess abdominal fat in HIV-associated lipodystrophy, marketed under the brand name Egrifta. That approval applies only to the specific clinical indication. This Elixser product is research-grade material intended for laboratory research only — not the FDA-approved drug product, not for human use, and not for any indication outside the original research context.
Every lot is tested by reverse-phase HPLC and certified at ≥99% purity. The Certificate of Analysis lists the exact lot purity (most lots run between 99.5% and 99.9%). Your COA ships with the vial and is also retrievable by lot number through our online verifier.
Testing is done by BioRegen Analytical, an independent third-party lab. Every batch goes through HPLC purity, LC-MS identity confirmation, sterility screening, and LAL endotoxin testing. The signed Certificate of Analysis ships with each vial. Same lot number, same COA, every time.
Made in the USA. Synthesized in a US cGMP-aligned facility. Tested by a US-based independent lab. Shipped from US fulfillment.
Orders ship via 2-day expedited delivery from US fulfillment. Free over $150. Vials are sealed, packaged with insulation, and shipped in tamper-evident packaging. Tracking number is sent the same day your order leaves the warehouse.
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